TY - BOOK AU - Weinberg,Robert A. TI - The biology of cancer SN - 0815340788 AV - RC268.4 .W45 2007 PY - 2007/// CY - New York PB - Garland Science KW - Cancer KW - Molecular aspects KW - Genetic aspects KW - Cancer cells KW - Neoplasms KW - genetics KW - Cell Transformation, Neoplastic KW - Genes, Neoplasm N1 - Includes bibliographical references and index; The biology and genetics of cells and organisms -- The nature of cancer -- Tumor viruses -- Cellular oncogenes -- Growth factors and their receptors -- Cytoplasmic signaling circuitry programs many of the traits of cancer -- Tumor suppressor genes -- pRb and control of the cell cycle clock -- p53 and apoptosis: master guardian and executioner -- Eternal life: cell immortalization and tumorigenesis -- Multistep tumorigenesis -- Maintenance of genomic integrity and the development of cancer -- Dialogue replaces monologue: heterotypic interactions and the biology of angiogenesis -- Moving out: invasion and metastasis -- Crowd control: tumor immunology and immunotherapy -- The rational treatment of cancer ER -