000			03852fam a22003614a 4500
001			3437536
003			KE-NaKCAU
005			20140425120054.0
008			020805s2002 caua b 001 0 eng
010			_a 2002012574
020			_a8177587579
035			_a(OCoLC)50323112
035			_a(OCoLC)ocm50323112
035			_a(NNC)3437536
040			_aDLC _cKE-NaKCAU _dDLC _dOrLoB-B
042			_apcc
050	0	0	_aQH324.2 _b.K72 2003
082	0	0	_a570/.285 _221
100	1		_aKrane, Dan E.
245	1	0	_aFundamental concepts of bioinformatics / _cDan E. Krane, Michael L. Raymer.
260			_aNew Delhi : _bPearson Education, _cc2003.
300			_axiii, 314 p. : _bill. ; _c24 cm.
504			_aIncludes bibliographical references and index.
505	0	0	_g1. _tMolecular Biology and Biological Chemistry -- _tThe Genetic Material -- _tGene Structure and Information Content -- _tProtein Structure and Function -- _tThe Nature of Chemical Bonds -- _tMolecular Biology Tools -- _tGenomic Information Content -- _g2. _tData Searches and Pairwise Alignments -- _tDot Plots -- _tSimple Alignments -- _tGaps -- _tScoring Matrices -- _tDynamic Programming: The Needleman and Wunsch Algorithm -- _tGlobal and Local Alignments -- _tDatabase Searches -- _tMultiple Sequence Alignments -- _g3. _tSubstitution Patterns -- _tPatterns of Substitutions within Genes -- _tEstimating Substitution Numbers -- _tVariations in Evolutionary Rates between Genes -- _tMolecular Clocks -- _tEvolution in Organelles -- _g4. _tDistance-Based Methods of Phylogenetics -- _tHistory of Molecular Phylogenetics -- _tAdvantages to Molecular Phylogenies -- _tPhylogenetic Trees -- _tDistance Matrix Methods -- _tMaximum Likelihood Approaches -- _tMultiple Sequence Alignments --
505	8	0	_g5. _tCharacter-Based Methods of Phylogenetics -- _tParsimony -- _tInferred Ancestral Sequences -- _tStrategies for Faster Searches -- _tConsensus Trees -- _tTree Confidence -- _tComparison of Phylogenetic Methods -- _tMolecular Phylogenies -- _g6. _tGenomics and Gene Recognition -- _tProkaryotic Genomes -- _tProkaryotic Gene Structure -- _tGC Content in Prokaryotic Genomes -- _tProkaryotic Gene Density -- _tEukaryotic Genomes -- _tEukaryotic Gene Structure -- _tOpen Reading Frames -- _tGC Content in Eukaryotic Genomes -- _tGene Expression -- _tTransposition -- _tRepetitive Elements -- _tEukaryotic Gene Density -- _g7. _tProtein and RNA Structure Prediction -- _tAmino Acids -- _tPolypeptide Composition -- _tSecondary Structure -- _tTertiary and Quaternary Structure -- _tAlgorithms for Modeling Protein Folding -- _tStructure Prediction -- _tPredicting RNA Secondary Structures -- _g8. _tProteomics -- _tFrom Genomes to Proteomes -- _tProtein Classification -- _tExperimental Techniques --
505	8	0	_tInhibitors and Drug Design -- _tLigand Screening -- _tX-Ray Crystal Structures -- _tNMR Structures -- _tEmpirical Methods and Prediction Techniques -- _tPost-Translational Modification Prediction. _gApp. 1. _tA Gentle Introduction to Computer Programming and Data Structures -- _gApp. 2. _tEnzyme Kinetics -- _gApp. 3. _tSample Programs in Perl.
520	1		_a"Fundamental Concepts of Bioinformatics is the first textbook co-authored by a biologist and computer scientist that is specifically designed to make bioinformatics accessible to undergraduates and prepare them for more advanced work. Students learn what programs are available for analyzing data, how to understand the basic algorithms that underlie these programs, what bioinformatic research is like, and other basic concepts.
520	8		_aInformation flows easily from one topic to the next, with enough detail to support the major concepts without overwhelming students."--BOOK JACKET.
650		0	_aBioinformatics. _98077
700	1		_aRaymer, Michael L.
900			_bTOC
942			_2lcc _cBK
999			_c12658 _d12658